Category: Uncategorized

  • Astigmatism

    Astigmatism is a common vision condition that causes blurred vision. It occurs when the cornea (the clear front cover of the eye) is irregularly shaped or sometimes because of the curvature of the lens inside the eye.

    An irregularly shaped cornea or lens prevents light from focusing properly on the retina, the light-sensitive surface at the back of the eye. As a result, vision becomes blurred at any distance. This can lead to eye discomfort and headaches.

    Astigmatism frequently occurs with other vision conditions like myopia (nearsightedness) and hyperopia (farsightedness). Together these vision conditions are referred to as refractive errors because they affect how the eyes bend or “refract” light.

    There are many causes to astigmatism. It can be hereditary and is usually present from birth. It can decrease or increase over time.

    comprehensive optometric examination will include testing for astigmatism. If necessary, your optometrist can provide eyeglasses or contact lenses that correct the astigmatism by altering the way light enters the eyes.

    Another option for treating astigmatism is a corneal procedure called orthokeratology (ortho-k). In this painless, noninvasive procedure, the patient wears a series of specially designed rigid contact lenses to gradually reshape the curvature of the cornea.

    Laser surgery can also treat some types of astigmatism. The laser changes the shape of the cornea by removing a small amount of eye tissue.

    Astigmatism

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    What causes astigmatism?

    Possible view through an astigmatic eye -- Image courtesy of Eyemaginations™

    The curvature of the cornea and lens bends the light entering the eye in order to focus it precisely on the retina at the back of the eye. In astigmatism, the surface of the cornea or lens has a somewhat different curvature.

    the surface of the cornea is shaped more like a football instead of round like a basketball, the eye is unable to focus light rays to a single point. Vision becomes out of focus at any distance.

    In addition, the curvature of the lens inside the eye can change, resulting in an increase or decrease in astigmatism. This change frequently occurs in adulthood and can precede the development of naturally occurring cataracts.

    Sometimes astigmatism may develop following an eye injury or eye surgery.

    Astigmatism also occurs due to a relatively rare condition called keratoconus in which the cornea becomes progressively thinner and cone-shaped. This results in a large amount of astigmatism, which causes poor vision that cannot be clearly corrected with eyeglasses. People with keratoconus usually need contact lenses for clear vision and eventually may need a corneal transplant.

    An optometrist can diagnose an astigmatism through a comprehensive eye examination. Testing for astigmatism measures how the eyes focus light and determines the power of any optical lenses needed to improve vision. This examination may include:

    • Visual acuity-When you read letters on a distance chart, you are measuring your visual acuity. Visual acuity is given as a fraction (for example, 20/40). The top number is the standardized testing distance (20 feet) and the bottom number is the smallest letter size read. A person with 20/40 visual acuity would have to get within 20 feet to read a letter that should be seen clearly at 40 feet. Normal distance visual acuity is 20/20.
    • Keratometry/Topography-A keratometer is the primary instrument used to measure the curvature of the cornea. By focusing a circle of light on the cornea and measuring its reflection, it is possible to determine the exact curvature of that area of the cornea’s surface. This measurement is particularly critical in determining the proper fit for contact lenses. A corneal topographer, which is gaining use, generates a contour map of the cornea and provides even more detail of the cornea’s shape.
    • Refraction-Using an instrument called a phoropter, your optometrist places a series of lenses in front of your eyes and measures how they focus light. This is performed using a handheld lighted instrument called a retinoscope or an automated instrument that evaluates the approximate focusing power of the eye. Based on your responses, the power is then refined to determine the lenses that allow the clearest vision. Despite improved technology, patient input remains integral in determining vision needs.

    With the information from these tests, your optometrist can determine if you have astigmatism. Your optometrist will use these findings, combined with those of other tests performed, to determine the power of any lens correction you need to provide clear, comfortable vision. Once testing is complete, your optometrist can discuss treatment options.

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    How is astigmatism treated?

    Eyeglasses are the primary choice for persons with astigmatism.

    People with astigmatism have several options to regain clear vision. They include:

    • Eyeglasses. People with astigmatism primarily choose eyeglasses to improve their vision. The eyeglasses contain a special cylindrical lens prescription that compensates for the astigmatism. This provides additional power in specific parts of the lens.

      Generally, a single-vision lens is prescribed to provide clear vision at all distances. However, patients over age 40 who have presbyopia may need a bifocal or progressive addition lens.

    • Contact lenses. Some people will have better vision with contact lenses rather than eyeglasses. Contact lenses may provide clearer vision and a wider field of view. However, since contact lenses are worn directly on the eyes, they require regular cleaning and care to safeguard eye health.

      Standard soft lenses may not be effective in correcting astigmatism. However, special toric soft contact lenses can correct for many types of astigmatism. Because rigid gas-permeable contact lenses maintain their regular shape while on the cornea, they can compensate for the cornea’s irregular shape and improve vision for people with astigmatism.

    • Orthokeratology. Orthokeratology (ortho-k) involves the fitting of a series of rigid contact lenses to reshape the cornea. The patient wears contact lenses for limited periods, such as overnight, and then removes them. People with moderate astigmatism may be able to temporarily obtain clear vision without lenses for most of their daily activities. Orthokeratology does not permanently improve vision. If patients stop wearing the retainer lenses, their vision may return to its original condition.
    • Laser and other refractive surgery procedures. Astigmatism can also be corrected by reshaping the cornea through LASIK (laser in situ keratomileusis) or PRK (photorefractive keratectomy). PRK removes tissue from the superficial and inner layers of the cornea. LASIK removes tissue only from the inner layer of the cornea.

    If you have an astigmatism, you have a wide range of options to correct your vision problem. In consultation with your optometrist, you can select the treatment that best meets your visual and lifestyle needs

  • CORONA VIRUS AND YOUR EYES

    Our eyes might play an important role in the spread and prevention of the new coronavirus outbreak seen throughout the world.

    For example, a Peking University physician believes he may have contracted the coronavirus while not wearing eye protection when treating patients. Medical officials, though, say while this is possible, it may be unlikely.

    To cut your personal risk of contracting the new coronavirus, avoid touching your eyes, nose or mouth with unwashed hands. It is the mucous membranes (membranes that line various cavities in the body) that are most susceptible to transmission of the virus.

    What is coronavirus?

    Reports of a new coronavirus (also referred to as COVID-19) first emerged in late December 2019 in Wuhan, China.

    Coronaviruses are a group of common viruses. Some affect only animals (such as bats, cats, camels and cattle), while others also affect people, according to the U.S. National Library of Medicine.

    COVID-19 can trigger ailments as minor as the common cold, or more consequential such as bronchitis, pneumonia and kidney failure. The most severe cases may be life-threatening. This is the seventh known type of coronavirus, according to the Centers for Disease Control and Prevention (CDC).

    How is the new coronavirus related to your eyes?

    Patients who have contracted the new coronavirus may have ocular symptoms.

    Conjunctivitis is an inflammation of the membrane covering the eyeball. It is often referred to as “pink eye.” Conjunctivitis often presents as an infected/red, “wet and weepy” eye.

    Viral conjunctivitis is known to present with upper respiratory infections (colds, flus, etc.) and may be a symptom of the COVID-19 virus. A recent study of hospitals across China, published in the New England Journal of Medicine , found “conjunctival congestion” or red, infected eyes in 9 of 1,099 patients (0.8%) with a confirmed diagnosis of coronavirus.

    A study in The Journal of Medical Virology  of 30 patients hospitalized for COVID-19 had only one patient diagnosed with conjunctivitis. Based on this information, the occurrence of conjunctivitis is low.

    IF YOU’RE NOT FEELING WELL… Call your family doctor. If you suspect you may have conjunctivitis, call an eye doctor near you. It is suggested that patients do not present to medical or eye care facilities without a prior phone call to help to decrease the possible spread of the virus. A phone call allows the health facility to prepare for your visit and diagnose and treat you in a proper manner.

    The relationship between the transmission of the coronavirus and your eyes is complicated.

    It’s thought that COVID-19 spreads from person to person mainly through airborne “respiratory droplets” produced when someone coughs or sneezes, much like the flu virus spreads, the CDC says. These droplets can land in the mouths or noses of people who are nearby, and possibly be inhaled into the lungs.

    Medical experts are unsure whether someone can contract this virus by touching a surface or object, such as a table or doorknob, that has COVID -19 on it and then touching their mouth, nose or possibly their eyes.

    Peking University respiratory specialist Wang Guangfa believes he contracted COVID-19 when he came into contact with patients at health clinics in China.

    Wang reported that his left eye became inflamed afterward, followed by a fever and a buildup of mucus in his nose and throat. He subsequently was diagnosed with the new coronavirus.

    According to the South China Morning Post , Wang thinks the virus entered his left eye because he wasn’t wearing protective eyewear.

    Dr. Jan Evans Patterson , professor of medicine and pathology in the Long School of Medicine’s infectious diseases division at UT Health San Antonio, confirms that a scenario like Wang’s could potentially happen.

    In Wang’s situation, she says, respiratory droplets from an infected person might have reached his eyes or other mucous membranes.

    Generally, though, transmission of COVID-19 comes with so many unknowns that it’s “plausible but unlikely” to contract it through hand-to-eye contact, says Dr. Stephen Thomas , chief of infectious diseases at SUNY Upstate Medical University in Syracuse, New York.

    How contagious is the new coronavirus?

    Currently, it’s not known how “easily or sustainably” the virus spreads from person to person, according to the CDC.

    Many large gatherings and events have been canceled or postponed as a public health measure to contain the spread of the new coronavirus. U.S. health officials have implemented these emergency measures as a best practice to contain the transmission of the virus.

    Schools have canceled classes and switched to online courses, and sports leagues and museums have closed as a precaution to avoid community spread.

    What are the symptoms of the new coronavirus?

    Symptoms of COVID-19 include a mild to severe respiratory illness accompanied by a fever, cough and breathing problems, according to the World Health Organization . Other symptoms include runny nose, sore throat and headache.

    Most people develop only mild symptoms. But some people, usually those who are older or have other medical complications, develop more severe symptoms, including pneumonia, which can be fatal.

    Symptoms normally show up two to 14 days after someone has been exposed to the virus.

    How is COVID-19 diagnosed?

    Health care professionals diagnose the coronavirus through lab tests of respiratory or blood samples or other bodily fluids.

    Is there a vaccine or treatment for the new coronavirus?

    So far, no vaccine or antiviral treatment has been identified. Therefore, the best method for limiting the spread of this virus is to quickly isolate people who have it (or are presumed to have it if they’ve been exposed to it) before they infect others, the Harvard Business Review says.

    How can you cut your risk of contracting coronavirus?

    The Centers for Disease Control and Prevention (CDC) has established a site with the most up-to-date information related to the coronavirus outbreak .

    The CDC’s recommended steps to prevent illness include:

    Clean your hands often

    Wash your hands often with soap and water for at least 20 seconds especially after you have been in a public place, eaten, used the restroom, blown your nose, coughed or sneezed.Avoid touching your eyes, nose and mouth as much as possible, but especially with unwashed hands.

    Reduce your exposure

    Avoid close contact with people who are sick.Stay home if you’re sick — except to get medical care.

    Cover coughs and sneezes

    Cover your mouth and nose with a tissue when you cough or sneeze or use the inside of your elbow.Throw used tissues in the trash.Immediately wash your hands with soap and water for at least 20 seconds.Wear a face mask that covers your mouth and nose if you are sick.

    If you are NOT sick: You do not need to wear a face mask unless you are caring for someone who is sick (and they are not able to wear a face mask). Face masks may be in short supply and they should be saved for health care workers, people who are sick and caregivers.

    Clean and disinfect surfaces

    Current evidence suggests that novel coronavirus may remain viable for hours to days on surfaces made from a variety of materials, the CDC reports. Cleaning of visibly dirty surfaces followed by disinfection is a best practice measure for prevention of COVID-19 and other viral respiratory illnesses in households and community settings.

    At least some coronavirus can potentially remain viable — capable of infecting a person — for up to 24 hours on cardboard and up to three days on plastic and stainless steel, The Washington Post  reports, citing research  by a laboratory that is part of the National Institute of Allergy and Infectious Diseases.

    How to dress to limit exposure

    According to the World Health Organization, if you have the potential of being exposed to a person with coronavirus, you should be equipped with protective eyewear, a surgical mask, medical gown, medical gloves and a disposable respirator.

    For more information, call us on tel: 07030000001 or visit our website: eyeclinic.professional.com.ng

  • Lagos Population Distribution

    Rank LGA Population
    1 Alimosho 5,700,714
    2 Ajeromi-Ifelodun 1,746,634
    3 Kosofe 665,998
    4 Mushin, Lagos 833,543
    5 Oshodi-Isolo 621,789
    6 Ojo 598,332
    7 Ikorodu 535,811
    8 Surulere 504,409
    9 Agege 461,123
    10 Ifako-Ijaiye 428,812
    11 Somolu 402,992
    12 Amuwo-Odofin 318,576
    13 Lagos Mainland 317,980
    14 Ikeja 313,333
    15 Eti-Osa 287,958
    16 Badagry 241,437
    17 Apapa 217,661
    18 Lagos Island 209,665
    19 Epe 181,715
    20 Ibeju-Lekki 117,542
    Lagos State
  • BILATERAL RETINITIS FOLLOWING TYPHOID FEVER

    Abstract

    Background

    Post typhoid fever immune related reactions affecting the eye is a rare finding which can have various presentations in which typhoid retinopathy is not a well recognized sequelae.

    Case presentation

    Here we present a case of 59 year old male who presented with right eye sudden painless loss of vision 4 weeks after typhoid fever which was diagnosed and treated successfully. His BCVA was 2/60 in right eye and 6/6 in left eye. Fundus examination showed retinitis along with macular serous detachment in right eye and retinitis in left eye. Significant improvement in BCVA in right eye was observed after treatment with oral steroid with resolving retinitis lesions. Diagnosis of post typhoid immune mediated retinitis was made with good resolution following treatment.

    Conclusions

    Immune mediated retinitis is a rare sequelae to typhoid infection which can be successfully treated with systemic steroids with good resolution of the lesions.

    Keywords: Post typhoid fever, Immune mediated, Typhoid retinopathy, Retinitis

    Background

    Typhoid or enteric fever is a systemic disease which is characterized by fever and abdominal pain caused due to dissemination of Salmonella typhi or paratyphi. It is transmitted by food or water due to fecal contamination by ill or asymptomatic chronic carriers. A high incidence of typhoid fever in developing countries correlates with poor sanitation and lack of access to clean drinking water []. Ocular manifestations of typhoid fever are rare and include lid edema or abscess, dacryoadenitis, conjunctival petechiae or chemosis, corneal ulceration, uveitis, vitreous haemorrhage, retinal haemorrhage and detachment, stellate maculopathy, pigmentary retinopathy, optic neuritis, internal or external ophthalmoplegia, orbital haemorrhage or abscess. These complications are caused either by direct invasion of the organisms into the ocular tissue, or by hypersensitivity reaction such as vitreous haemorrhage after typhoid vaccination []. Here we are presenting a case of retinitis with macular serous detachment developing post typhoid fever.

    Case report

    A 59 year old male presented to our hospital 1 week after experiencing diminution of vision in the right eye. He gave a history of typhoid fever 4 weeks prior to presentation for which Widal test was performed to confirm diagnosis. The test results showed significant titres for ‘O’ antigen (>1:80) and ‘H’ antigen (>1:160) and negative for ‘AH’ and ‘BH’ antigens. He was subsequently started on oral Ofloxacin 400 mg twice daily for 2 weeks following which fever subsided. There was no known history of diabetes mellitus or hypertension. On ocular examination his best corrected visual acuity was 2/60 in the right eye and 6/6 in left eye. Anterior segment findings were unremarkable with IOP being within normal range for both eyes. Fundus examination of right eye showed white fluffy lesions along the superior and inferior arcades with superficial haemorrhages in around the macula with a macular star suggestive of retinitis (Fig. 1a). Left eye fundus showed few dispersed retinitis lesions with superficial haemorrhage along the superior arcade with intact foveal reflex (Fig. 1b). On optical coherence tomography of right eye underlying macular serous retinal detachment was noted (Fig. 2a). Blood tests were done to rule out VDRL and HIV status. X-cyton analysis of the anterior chamber aspirate was negative for organisms like Mycobacterial Tuberculosis, Toxoplasma Gondii, Hepes Simplex Virus, Cytomegalovirus and Varicella Zoster Virus. After analysis of the reports diagnosis of post typhoid retinitis in both eyes was made. Patient was started on oral prednisolone 1 mg/kg body weight which was tapered over 2 months along with monitoring of systemic and ocular health. Patient came for follow up every 2 weeks for 3 months. Every visit fundus photo was documented. After 2 months of initiating treatment there was an improvement in the BCVA in right eye to 6/6 which was maintained on further visits. Fundus examination revealed resolving lesions in both eyes (Fig. 3a, b) and OCT of the right eye showed resolution of the serous detachment (Fig. 2b).

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    a Fundus photo of right eye with white fluffy lesions suggestive of retinitis in the superior and inferior temporal arcades with macular star. b Fundus photo of left eye with white fluffy retinitis lesions in the superior temporal arcade

    An external file that holds a picture, illustration, etc. Object name is 40942_2017_65_Fig2_HTML.jpg

    a Pre treatment OCT of right eye suggestive of macular edema. b A normal OCT photo of right eye post treatment

    An external file that holds a picture, illustration, etc. Object name is 40942_2017_65_Fig3_HTML.jpg

    a Post treatment fundus photo of right eye showing resolved retinitis lesions with few dispersed hard exudates. b Post treatment fundus photo of left eye with resolved retinitis lesions

    Retinitis is characterized by confluent areas of retinal whitening which progresses along the retinal blood vessels, often associated with intraretinal hemorrhages and hard exudates. A significant number of retinitis cases are thought to be idiopathic in etiology but a small proportion of cases are infectious in etiology such as Toxoplasma gondii (toxoplasmosis), Leptospira spp. (leptospirosis), Mycobacterium tuberculosis (tuberculosis) and other viral and fungal etiologies []. Non infectious causes of retinitis include sarcoidosis, Behcet’s disease. Infectious causes are usually unilateral and may be associated with mild vitritis. Patients can present with Neuroretinitis like picture with optic disc edema and macular hard exudates []. The macular star becomes prominent over first 3 weeks with neuroretinitis resolving over 6–8 weeks []. Leakage from the optic nerve head can lead to retinal swelling, exudation and edema, whereas retinal venous occlusion due to vasculitis results in intraretinal haemorrhage, cotton wool spots and retinal and optic nerve head edema []. It was postulated that microbial pathogens may be responsible for immune mediated ocular and systemic pathology through postinfectious immunological effects. These may be due to molecular mimicry eliciting an immune response that cross react with self antigens. Even though active infection is an unusual cause of retinal vasculitis, it is possible that many idiopathic and systemic disease associated cases are precipitated by previous encounters with microbes bearing DNA sequence homologous to retinal and vascular autoantigens. Similarity between S-antigen and peptides derived from yeast, E. coli, and Hepatitis B virus was found and there was an ability of these microbial peptides to elicit an immune response post infection []. Immune mediated retinitis is a clinical diagnosis most often when there is past history of infection few weeks or days prior to the onset of ocular manifestations. In this case, treatment with oral steroids was initiated due to inflammation of the retina, especially the macula which caused decrease in vision. By taking into consideration the time of onset of ocular presentation, previous history of typhoid fever and the response to oral steroids; the most likely diagnosis was post typhoid fever immune mediated retinitis with macular neurosensory detachment in the right eye and retinitis in left eye. In our case as the disc edema was not prominent, neuroretinitis was not considered as the diagnosis. Similar case reports by Relhan et al. [] and Laul et al. [] showed immune mediated response post typhoid fever presenting with neuroretinitis, vasculitis and macular detachment. Successful treatment with steroids was seen in them. Fusco et al. [] reported a case of bilateral chorioretinitis and stellate maculopathy post typhoid fever. However, in our case Xcyton analysis was done to rule out possible infectious retinitis before initiating steroid therapy, as it could exacerbate non immune mediated retinitis. Xcyton multiplex PCR analysis even though has the advantage of increasing the diagnostic yield it has certain disadvantages like false positive and negative results due to cross reactivity and preferential amplification, negative internal control if there is high amount of a particular target causing exhaustion of reagents and high cost.

    Conclusion

    Immune mediated retinitis can occur following systemic infection and can be managed with steroids followed by good resolution of the lesions. PCR analysis of the aqueous is a rapid diagnostic tool wherein multiple organisms can be detected and sight threatening bacterial and viral infections can be ruled out before initiation of steroid therapy.

    Authors’ contributions

    PM carried out AC tap for Xcyton analysis, did the manuscript editing and review, TT did the data acquisition, literature search and manuscript preparation, GG did the data acquisition and analysis and manuscript review, SA did the data acquisition and analysis. All authors read and approved the final manuscript.

    Acknowledgements

    None.

    Competing interests

    The authors declare that they have no competing interests.

    Contributor Information

    M. Prabhushanker, moc.liamg@reknahsuhbarprd.

    Tasneem T. Topiwalla, moc.liamg@spotsat.

    Geetha Ganesan, moc.liamg@nasenageeg.

    Sripal Appandaraj, moc.liamg@rd.lapirs.

    References

    1. Pegeus DA, Miller SI. Salmonellosis. In: Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, editors. Harrison’s principles of internal medicine. 18. New York: McGraw Hill; 2012. pp. 1274–1285. []
    2. Curtis TH, Whealer DT. Infectious diseases. In: Roy FH, Fraunfelder FW, Fraunfelder FT, editors. Current ocular therapy. 6. London: Elsevier Saunders; 2008. pp. 92–94. []
    3. Jacobs DA, Guercio JR, Balcer LJ. Inflammatory optic neuropathies and neuroretinitis. In: Yanoff M, Duker JS, editors. Ophthalmology. 4. London: Elsevier Saunders; 2014. pp. 879–883. []
    4. Houghton OM, Brown GC, Brown MM. Coexistent optic nerve and macular abnormalities. In: Yanoff M, Duker JS, editors. Ophthalmology. 4. London: Elsevier Saunders; 2014. pp. 632–637. []
    5. Hughes EH, Dick AD. The pathology and pathogenesis of retinal vasculitis. Neuropathol Appl Neurobiol. 2003;29:325–340. doi: 10.1046/j.1365-2990.2003.00499.x. [PubMed] [CrossRef[]
    6. Relhan N, Pathengay A, Albini T, Priya K, Jalali S, Flynn HW, et al. A case of vasculitis, retinitis and macular neurosensory detachment presenting post typhoid fever. J Ophthalmic Inflamm Infect. 2014;4:23. doi: 10.1186/s12348-014-0023-y. [PMC free article] [PubMed] [CrossRef[]
    7. Laul R, Atif Ali MIR, Shafi S. Typhoid aftermath: presenting as vasculitis, neuroretinitis and macular neurosensory detachment. Int J Med Res Health Sci. 2015;4:737–739. doi: 10.5958/2319-5886.2015.00143.5. [CrossRef[]
    8. Fusco R, Magli A, Guacci P. Stellate maculopathy due to Salmonella typhiOphthalmologica. 1986;192:154–158. doi: 10.1159/000309629. [PubMed] [CrossRef[
  • WHAT IS GLAUCOMA?

    Glaucoma is a condition that causes damage to your eye’s optic nerve and gets worse over time. It’s often linked to a buildup of pressure inside your eye. Glaucoma tends to be inherited and may not show up until later in life.

    The increased pressure, called intraocular pressure, can damage the optic nerve, which transmits images to your brain. If the damage continues, glaucoma can lead to permanent vision loss. Without treatment, glaucoma can cause total permanent blindness within a few years.

    Most people with glaucoma have no early symptoms or pain. You need to see your eye doctor regularly so she can diagnose and treat glaucoma before long-term visual loss happens.

    If you’re over age 40 and have a family history of the disease, you should get a complete eye examfrom an eye doctor every 1 to 2 years. If you have health problems like diabetes or a family history of glaucoma or are at risk for other eyediseases, you may need to go more often.

    What Causes Glaucoma?

    It’s the result of an intrinsic deterioration of the optic nerve, which leads to high fluid pressure on the front part of the eye.

    Normally, the fluid, called aqueous humor, flows out of your eye through a mesh-like channel. If this channel gets blocked, the liquid builds up. The reason for the blockage is unknown, but doctors do know it can be inherited, meaning it’s passed from parents to children.

    Less common causes include a blunt or chemical injury to your eye, severe eye infection, blocked blood vessels inside the eye, and inflammatory conditions. It’s rare, but sometimes eye surgery to correct another condition can bring it on. It usually affects both eyes, but it may be worse in one than the other.

    What Are the Types of Glaucoma?

    There are two main kinds:

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    Open-angle glaucoma. It’s the most common type. Your doctor may also call it wide-angle glaucoma. The drain structure in your eye — it’s called the trabecular meshwork — looks normal, but fluid doesn’t flow out like it should.

    Angle-closure glaucoma. It’s less common in the West than in Asia. You may also hear it called acute or chronic angle-closure or narrow-angle glaucoma. Your eye doesn’t drain right because the drain space between your iris and cornea becomes too narrow. This can cause a sudden buildup of pressure in your eye. It’s also linked to farsightedness and cataracts, a clouding of the lens inside your eye.

    Who Gets Glaucoma?

    It mostly affects adults over 40, but young adults, children, and even infants can have it. African-Americans tend to get it more often, when they’re younger, and with greater vision loss.

    You’re more likely to get it if you:

    • Are of African-American, Irish, Russian, Japanese, Hispanic, Inuit, or Scandinavian descent
    • Are over 40
    • Have a family history of glaucoma
    • Have poor vision
    • Have diabetes
    • Take certain steroid medications, like prednisone
    • Have had trauma to the eye or eyes

    What Are the Symptoms?

    Most people don’t have any. The first sign is often a loss of peripheral, or side, vision. That can go unnoticed until late in the disease. That’s why glaucoma is often called the “sneak thief of vision.”

    Detecting glaucoma early is one reason you should have a complete exam with an eye specialist every 1 to 2 years. Occasionally, pressure inside the eye can rise to severe levels. In these cases, you may have sudden eye painheadache, blurred vision, or the appearance of halos around lights.

    If you have any of the following symptoms, seek immediate medical care:

    • Seeing halos around lights
    • Vision loss
    • Redness in the eye
    • Eye that looks hazy (particularly in infants)
    • Nausea or vomiting
    • Eye pain
    • Narrowed vision (tunnel vision)

    How Is It Diagnosed?

    Your eye doctor will use drops to open (he’ll call it dilate) your pupils. Then he’ll test your vision and examine your eyes. He’ll check your optic nerve, and if you have glaucoma, it will look a certain way. He may take photographs of the nerve to help him track your disease over time. He’ll do a test called tonometry to check your eye pressure. He’ll also do a visual field test, if necessary, to figure out if you’ve lost your side, or peripheral, vision. Glaucoma tests are painless and take very little time.

    How Is Glaucoma Treated?

    Your doctor may use prescription eye drops, laser surgery, or microsurgery to lower pressure in the eye.

    Eye drops. These either reduce the formation of fluid in the eye or increase its outflow, thereby lowering eye pressure. Side effects may include allergies, redness, stinging, blurred vision, and irritated eyes. Some glaucoma drugs may affect your heart and lungs. Be sure to tell your doctor about any other medications you’re taking or are allergic to.

    Laser surgery. This procedure can slightly increase the flow of the fluid from the eye for people with open-angle glaucoma. It can stop fluid blockage if you have angle-closure glaucoma. Procedures include:

    • Trabeculoplasty: Opens the drainage area
    • Iridotomy: Makes a tiny hole in the iris to let fluid flow more freely
    • Cyclophotocoagulation: Treats areas of the middle layer of your eye to reduce fluid production

    Microsurgery. In a procedure called a trabeculectomy, the doctor creates a new channel to drain the fluid and ease eye pressure. Sometimes this form of glaucoma surgery fails and has to be redone. Your doctor might implant a tube to help drain fluid. Surgery can cause temporary or permanent vision loss, as well as bleeding or infection.

    Open-angle glaucoma is most often treated with various combinations of eye drops, laser trabeculoplasty, and microsurgery. Doctors in the U.S. tend to start with medications, but there’s evidence that early laser surgery or microsurgery could work better for some people.

    Infant or congenital glaucoma — meaning you are born with it — is primarily treated with surgery, because the cause of the problem is a very distorted drainage system.

    Talk to your eye doctor to find out which glaucoma treatment is right for you.

    Can You Prevent Glaucoma?

    No. But if you diagnose and treat it early, you can control the disease.

    What’s the Outlook?

    At this time, lost vision can’t be restored. However, lowering eye pressure can help preserve the sight you have. Most people with glaucoma who follow their treatment plan and have regular eye exams don’t go blind.

  • Sweet sleep: Dealing with and overcoming sleep disorders – by Anna Kucirkova

    Sleep.

    We often take it for granted, expecting that every night we’ll drift into sweet slumber. But for millions of people around the world, sleep is a challenge. Due to sleep disorders, they find themselves unable to sleep, or worse.

    But what exactly are sleep disorders? And what causes them?

    In this post, we’re going to break down both the what and why of sleep disorders, as well as explain the effects of lack of sleep on the human body.

    Ready? Let’s dive in.


    What Is A Sleep Disorder?

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    Put simply, a sleep disorder is a change in the way you sleep. Instead of sleeping well and getting a good night’s rest, new, unhealthy sleep patterns are introduced into your life, altering the very fabric of your sleep.

    Sleep problems are widespread, with approximately 10-20% of people saying that they struggle with significant sleep problems, and another 33% of adults reporting insomnia-like symptoms.

    Sleep disorders can be grouped in a variety of ways, including difficulty falling asleep, feeling extra sleepy during the day, having trouble breathing at night, problems with your natural sleep-wake cycles, and behaviors at night while sleeping.

    How do you know if you have a sleep disorder? There are some common symptoms that are signs that something is greatly amiss with your sleep:

    • Excessive sleepiness during the day
    • Irregular breathing patterns at night
    • Irregular movements at night
    • Difficulty falling asleep

    If you struggle with any of these symptoms, there is a good chance that you’re struggling with some form of sleep disorder.


    What Are Some Common Sleep Disorders?

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    There are a variety of common sleep disorders which affect millions of people around the world.

    These disorders include:

    Insomnia

    Perhaps the most well-known of all sleep disorders, insomnia is characterized by the inability to either fall asleep or stay asleep, resulting in a person getting insufficient sleep.

    For most people with insomnia, it takes more than 20-30 minutes to fall asleep (or fall back asleep). If this happens at least three times per week for more than three months it is called “chronic insomnia”.

    Approximately 10% of all adults are officially diagnosed with insomnia, making it the most common sleep disorder.

    Insomnia is often treated with either Cognitive Behavioral Therapy or medication.

    Sleep Apnea

    Sleep apnea is an extreme form of snoring. It is a chronic medical condition in which a person stops breathing repeatedly while they are sleeping. This stoppage of breath can last 10 seconds or more and can cause both oxygen levels to drop and the person to temporarily awake from sleep.

    Typically, sleep apnea is caused by one of two things. First, it can be the result of an obstruction of the upper airway. This is called “obstructive sleep apnea”. It can also be caused by the brain itself failing to initiate breathing, which is called “central sleep apnea”.

    If left untreated, the health effects of sleep apnea can be significant, including:

    All of these are in addition to the extreme sleepiness which sleep apnea typically causes.

    Sleep apnea is typically treated with a CPAP device, which forces a steady stream of air into a person’s nose to ensure that they keep breathing.

    If you want to know more about sleep apnea, here’s a helpful video:

    https://youtu.be/i6lxO6W2-m8

    Restless Leg Syndrome

    Sleep Apnea

    Restless leg syndrome (RLS) is a disorder in which the person feels the need to constantly move while in bed, particularly their legs. People often describe the sensation as aching, burning, tingling, or even feeling like bugs are crawling on their legs. These symptoms can make it extremely difficult to fall asleep and stay asleep.

    There are many causes of restless legs, including pregnancy, iron deficiency, and obesity.

    RLS can be treated through exercise, a reduction in caffeine or alcohol, and in severe cases, medication.


    Circadian Rhythm Disorders

    Your circadian rhythm is your body’s internal clock, telling you when to wake up and when to go to sleep. Circadian rhythm disorders occur when a person’s internal clock is out of sync with the external world.

    For example, being wide awake at 2:00 AM may indicate that your circadian rhythm has gotten out of sync with the light-dark cycle.

    Typically, these disorders happen due to shifting work, jet lag, advanced or delayed sleep phase syndrome, or blindness. The mismatch between the circadian rhythm and the external cues can result in insomnia or extreme sleepiness.

    Circadian rhythm disorders can be treated with medication or natural supplements such as melatonin.


    Parasomnias

    Parasomnias are sleep disorders characterized by strange, abnormal sleep behaviors. These behaviors can be complex and are done unconsciously, as the person is fully asleep. These behaviors can include everything from sleep terrors to sleepwalking to sleep eating to even sleep sex.

    There can be a number of underlying causes, including sleep apnea. Thankfully, these disorders can often be treated with medications such as melatonin or clonazepam.


    Sleep Paralysis

    Sleep paralysis involves the temporary inability to move as a person moves from sleep to wakefulness or vice versa. This temporary feeling of paralysis can be quite frightening and often involves hallucinations as well. The disorder is common, with around 25% of people experiencing it at least once.

    If necessary, sleep paralysis can be treated with medication.


    Narcolepsy

    There are four symptoms typically associated with narcolepsy:

    • Excessive sleepiness during the day
    • Cataplexy (the sudden loss of muscle tone in response to a particular stimulus such as laughter or surprise)
    • Sleep paralysis
    • Hypnagogic hallucinations (very vivid hallucinations)

    The result of these symptoms can be a person seemingly falling asleep in an instant at any point in time.

    Narcolepsy is most often treated with medications.

    For more information on narcolepsy, here’s a helpful video:

    Chronic Fatigue Syndrome

    Chronic Fatigue Syndrome (CFS) is an ongoing, unexplained fatigue that is not lessened by rest or sleep. It may be worsened through physical or mental activity, and the results can be extreme, causing a person to be practically incapacitated.

    The fatigue can be so extreme that a person is forced to adapt their daily schedule so that they can preserve as much energy as possible.

    Before a person can be diagnosed with CFS, other underlying causes, such as sleep apnea, must be ruled out.


    What Are The Effects Of Lack Of Sleep?

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    There are numerous detrimental effects of lack of sleep.

    • Not getting enough sleep can cause you to have memory problems. Sleep is essential to forming memories and not getting enough sleep can affect both your long-term and your short-term memory.
    • Sleeplessness can also result in difficulty concentrating and problem-solving.
    • Mood changes are a common side effect of lack of sleep. When you don’t get enough sleep, your emotions are on a hair-trigger and can lead to depression or anxiety.
    • If you sleep less than five hours per night, your risk of high blood pressure greatly increases.
    • A lack of sleep is detrimental to your immune system, making you much more vulnerable to viruses that cause the common cold and the flu.
    • Weight gain is a common side effect of not getting enough sleep. When you’re sleep-deprived, your brain doesn’t send the normal signals to your body that you’re full, resulting in overeating.
    • Many people who don’t sleep enough find themselves experiencing a low sex drive. In men, this may be caused by a drop in overall testosterone levels.
    • A lack of sleep can affect your body’s ability to control insulin levels, which is a blood-sugar-lowering hormone. Those who don’t get enough sleep often have higher levels of blood sugar, which can eventually result in Type-2 diabetes.
    • When you don’t get enough sleep, your balance and coordination are affected, making you much more prone to falling.

    Don’t Neglect Your Sleep

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    Sleep is absolutely essential for your body to function properly. When you don’t get enough sleep, all manner of problems arises, affecting your life in significantly negative ways. You should do whatever is necessary to get as much sleep as you need.

    If you suspect that you have a sleep disorder, talk to a health professional today. Left untreated, sleep disorders can wreak havoc on your life.

    Don’t let a sleep disorder keep you from living the life you deserve. Get treatment today.

  • Eye twitching: 8 causes and remedies

    What is eye twitching?

    Eye twitching — which actually is twitching of an eyelid — is common and harmless.

    Most eye twitching lasts only a few minutes, but sometimes an eyelid twitch can persist for days or longer. If you have an eye twitch that doesn’t go away relatively quickly, see an eye doctor.

    The medical term for eye twitching is myokymia.

    If you experience eye twitching that doesn’t go away, this could signal a serious neurological condition affecting the eyelid — such as blogs to spasm or hemifacial spasm.

    These relatively rare conditions are more obvious and severe than common eye twitching and should be evaluated immediately by an eye doctor.

    What causes eye twitching?

    Triggers of eye twitching include:

    • Stress
    • Fatigue
    • Eye strain
    • Caffeine
    • Alcohol
    • Dry eyes
    • Nutrition problems
    • Allergies

    If you experience eye twitching, take a close look at this list and note which of these potential triggers might apply to you. Sometimes, making minor changes to your diet and lifestyle can significantly reduce your risk of eye twitching or help make an eyelid twitch disappear.

    Eye twitching causes and fixes

    1. Stress

    Stress is probably the most common cause of eye twitching. Yoga, breathing exercises, spending time with friends or pets and getting more down time into your schedule are ways to reduce stress that may be causing your eyelid twitch.

    2. Fatigue

    Lack of sleep, whether because of stress or some other reason, can trigger eye twitching. Catching up on your sleep and having a consistent sleep schedule can help.

    3. Eye strain

    Eye strain — particularly digital eye strain from overuse of computers, tablets and smartphones — also is a common cause of eyelid twitching.

    Follow the “20-20-20 rule” when using digital devices: Every 20 minutes, look away from your screen and allow your eyes to focus on a distant object (at least 20 feet away) for 20 seconds or longer. This reduces fatigue that may trigger eye twitching.

    Also, ask your eye doctor about computer eyeglasses to relieve digital eye strain.

    EYE CARE

    Eye twitching: 8 causes and remedies

    Woman rubbing her eyes to deal with eyelid twitching.
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    What is eye twitching?

    Eye twitching — which actually is twitching of an eyelid — is common and harmless.

    Most eye twitching lasts only a few minutes, but sometimes an eyelid twitch can persist for days or longer. If you have an eye twitch that doesn’t go away relatively quickly, see an eye doctor.

    The medical term for eye twitching is myokymia.

    If you experience eye twitching that doesn’t go away, this could signal a serious neurological condition affecting the eyelid — such as blepharospasm

    or hemifacial spasm

    . These relatively rare conditions are more obvious and severe than common eye twitching and should be evaluated immediately by an eye doctor.

    What causes eye twitching?

    Triggers of eye twitching include:

    • Stress
    • Fatigue
    • Eye strain
    • Caffeine
    • Alcohol
    • Dry eyes
    • Nutrition problems
    • Allergies

    If you experience eye twitching, take a close look at this list and note which of these potential triggers might apply to you. Sometimes, making minor changes to your diet and lifestyle can significantly reduce your risk of eye twitching or help make an eyelid twitch disappear.

    Eyelid twitching animation

    When your eyelid is twitching, you might think everyone else can see it. But most eye twitches are subtle and are not easily seen by others.

    Eye twitching causes and fixes

    1. Stress

    Stress is probably the most common cause of eye twitching. Yoga, breathing exercises, spending time with friends or pets and getting more down time into your schedule are ways to reduce stress that may be causing your eyelid twitch.

    2. Fatigue

    Lack of sleep, whether because of stress or some other reason, can trigger eye twitching. Catching up on your sleep and having a consistent sleep schedule can help.

    3. Eye strain

    Eye strain — particularly digital eye strain from overuse of computers, tablets and smartphones — also is a common cause of eyelid twitching.

    Follow the “20-20-20 rule” when using digital devices: Every 20 minutes, look away from your screen and allow your eyes to focus on a distant object (at least 20 feet away) for 20 seconds or longer. This reduces fatigue that may trigger eye twitching.

    Also, ask your eye doctor about computer eyeglasses to relieve digital eye strain.

    Infographic: How To Stop  Eye Twitching [Enlarge]

    4. Caffeine

    Too much caffeine can trigger eye twitching. Try cutting back on coffee, tea and soft drinks (or switch to decaffeinated versions) for a week or two and see if your eye twitching disappears.

    5. Alcohol

    If you experience eye twitching after drinking beer, wine or liquor, try abstaining for a while, since alcohol consumption may cause eyelids to twitch.

    6. Dry eyes

    Many adults experience dry eyes, especially after age 50. Dry eyes also are very common among people who use computers, take certain medications (especially antihistamines and some antidepressants), wear contact lenses and consume caffeine and/or alcohol.

    If you have a twitching eyelid and your eyes feel gritty or dry, see your eye doctor for a dry eye evaluation. Restoring moisture to the surface of your eye may stop the eye twitching and decrease the risk of twitching in the future.

    7. Nutrition problems

    Some reports suggest a lack of certain nutritional elements, such as magnesium, can trigger eyelid spasms. Although these reports are not conclusive, this may be another possible cause of eye twitching.

    If you are concerned that your diet may not be supplying all the nutrients you need for healthy vision, discuss this with your eye doctor before purchasing over-the-counter nutritional supplements.

    8. Allergies

    People with eye allergies can have itching, swelling and watery eyes. Rubbing your eyes because of allergy symptoms releases histamine into your eyelid tissues and tear film, which may cause eye twitching.

    Sometimes, over-the-counter eye drops formulated to reduce allergy symptoms can be helpful. But antihistamines in these drops can cause dry eyes. It’s best to consult your eye doctor to make sure you’re doing the right thing for your eyes if you experience allergy symptoms and eye twitching.

    Another way to stop eye twitching: Botox

    In rare cases, some eye twitching just won’t go away, despite applying the remedies above.

    Persistent eyelids twitches can be treated with Botox injections to stop the involuntary muscle contractions in the eyelid that cause the twitching.

    When to see an eye doctor

    See an eye doctor immediately if you experience persistent eye twitching, sudden changes in appearance or movement of half your face (including your eyelids), or if both eyelids clamp down so tight it’s impossible to open your eyes. These can be signs of a serious condition.

  • HAPPY EASTER

    The management and staff of Eyeupdate Eye Clinic & Optical Supplies wish you a Happy Easter season.

    God bless you

     

  • When to see an Eye-doctor

    When to see an eye Doctor

    1, You always have a headache
    2, Your eye is infected
    3, There are bright flashes or floaters
    4, There is eye pain
    5, You have been squinting
    6, You have diabetes or it is in the family
    7, You have hypertension or it is in the family
    8, Excessive light sensitivity
    9, Your eyes are always red
    10, You spend so much time on computer or phone-screen
    11, If you have never had your eyes examined before

    What is eye examination?

    An eye examination consists of series of tests that your eye doctor will perform in order to determine the status of your eyes.
    The eye doctor will ask you to read professionally crafted letters at both far and near and take note of what you might see and what you might not see. Then he will carry out some external and internal tests to ascertain the integrity of the ocular structures. After that, he will review the results of the tests and discuss the result with you and what options are available and what the implications would be.

    Then you would be given treatment based on the diagnosis and would be placed on a follow-up if need be.

  • Cataract Surgery

    Cataract surgery, also called lens replacement surgery, is the removal of the natural lens of the eye (also called “crystalline lens”) that has developed an opacification, which is referred to as a cataract, and its replacement with an intraocular lens. Metabolic changes of the crystalline lens fibers over time lead to the development of the cataract, causing impairment or loss of vision. Some infants are born with congenital cataracts, and certain environmental factors may also lead to cataract formation. Early symptoms may include strong glare from lights and small light sources at night, and reduced acuity at low light levels.

    During cataract surgery, a patient’s cloudy natural cataract lens is removed, either by emulsification in place or by cutting it out. An artificial intraocular lens (IOL) implant is inserted (eye surgeons say that the lens is “implanted”) in its place. Cataract surgery is generally performed by an ophthalmologist in an ambulatory setting a surgical center or hospital rather than an inpatient setting,. Either topical, peribulbar, or retrobulbar local anesthesia is used, usually causing little or no discomfort to the patient.

    Well over 90% of operations are successful in restoring useful vision, with a low complication rate. Day care, high volume, minimally invasive, small incision phacoemulsification with quick post-op recovery has become the standard of care in cataract surgery all over the world.

    Types

    Two main types of surgical procedures are in common use throughout the world. The first procedure is phacoemulsification (phaco) and the second involves two different types of extracapsular cataract extraction (ECCE). In most surgeries, an intraocular lens is inserted. Foldable lenses are generally used for the 2-3mm phaco incision, while non-foldable lenses are placed through the larger extracapsular incision. The small incision size used in phacoemulsification (2-3mm) often allows “sutureless” incision closure. ECCE utilises a larger incision (10-12mm) and therefore usually requires stitching, and this in part led to the modification of ECCE known as manual small incision cataract surgery (MSICS).

    Cataract extraction using intracapsular cataract extraction (ICCE) has been superseded by phaco & ECCE, and is rarely performed.

    Phacoemulsification is the most commonly performed cataract procedure in the developed world. However, the high cost of a phacoemulsification machine and of the associated disposable equipment means that ECCE and MSICS remain the most commonly performed procedure in developing countries.

    Types of surgery

    Cataract surgery, using a temporal approach phacoemulsification probe (in right hand) and “chopper”(in left hand) being done under the operating microscope at a Navy medical center

    Cataract surgery recently performed, foldable IOL inserted. Note small incision and very slight hemorrhage to the right of the still dilated pupil.
    There are a number of different surgical techniques used in cataract surgery:

    Phacoemulsification (phaco) is the most common technique used in developed countries. It involves the use of a machine with an ultrasonic handpiece equipped with a titanium or steel tip. The tip vibrates at ultrasonic frequency (40,000 Hz) and the lens material is emulsified. A second fine instrument (sometimes called a “cracker” or “chopper”) may be used from a side port to facilitate cracking or chopping of the nucleus into smaller pieces. Fragmentation into smaller pieces makes emulsification easier, as well as the aspiration of cortical material (soft part of the lens around the nucleus). After phacoemulsification of the lens nucleus and cortical material is completed, a dual irrigation-aspiration (I-A) probe or a bimanual I-A system is used to aspirate out the remaining peripheral cortical material.
    Manual small incision cataract surgery (MSICS): This technique is an evolution of ECCE (see below) where the entire lens is expressed out of the eye through a self-sealing scleral tunnel wound. An appropriately constructed scleral tunnel is watertight and does not require suturing. The “small” in the title refers to the wound being relatively smaller than an ECCE, although it is still markedly larger than a phaco wound. Head-to-head trials of MSICS vs phaco in dense cataracts have found no difference in outcomes, but shorter operating time and significantly lower costs with MSICS.[medical citation needed]

    Nucleus of hypermature cataract after ECCE
    Extracapsular cataract extraction (ECCE): Extracapsular cataract extraction involves the removal of almost the entire natural lens while the elastic lens capsule (posterior capsule) is left intact to allow implantation of an intraocular lens.[1] It involves manual expression of the lens through a large (usually 10–12 mm) incision made in the cornea or sclera. Although it requires a larger incision and the use of stitches, the conventional method may be indicated for patients with very hard cataracts or other situations in which phacoemulsification is problematic.
    Intracapsular cataract extraction (ICCE) involves the removal of the lens and the surrounding lens capsule in one piece. The procedure has a relatively high rate of complications due to the large incision required and pressure placed on the vitreous body. It has therefore been largely superseded and is rarely performed in countries where operating microscopes and high-technology equipment are readily available.[1] After lens removal, an artificial plastic lens (an intraocular lens implant) can be placed in either the anterior chamber or sutured into the sulcus.
    Femtosecond laser-assisted cataract surgery has been shown to have no visual, refractive or safety benefit over manual phacoemulsification.[2][3]
    Cryoextraction is a form of ICCE that freezes the lens with a cryogenic substance such as liquid nitrogen.[4] In this technique, the cataract is extracted through use of a cryoextractor — a cryoprobe whose refrigerated tip adheres to and freezes tissue of the lens, permitting its removal. Although it is now used primarily for the removal of subluxated lenses, it was the favored form of cataract extraction from the late 1960s to the early 1980s.[5]

    Intraocular lenses

    Intraocular lens (IOL) implantation: After the removal of the cataract, an IOL is usually implanted into the eye, either through a small incision (1.8 mm to 2.8 mm) using a foldable IOL, or through an enlarged incision, using a PMMA lens. The foldable IOL, made of silicone or acrylic material of appropriate power is folded either using a holder/folder, or a proprietary insertion device provided along with the IOL. The lens implanted is inserted through the incision into the capsular bag within the posterior chamber (in-the-bag implantation). Sometimes, a sulcus implantation (in front or on top of the capsular bag but behind the iris) may be required because of posterior capsular tears or because of zonulodialysis. Implantation of posterior chamber IOL (PCIOL) in patients below 1 year of age is controversial due to rapid ocular growth at this age and the excessive amount of inflammation, which may be very difficult to control. Optical correction in these patients without intraocular lens (aphakic) is usually managed with either special contact lenses or glasses. Secondary implantation of IOL (placement of a lens implant as a second operation) may be considered later. New designs of multifocal intraocular lens are now available. These lenses allow focusing of rays from distant as well as near objects, working much like bifocal or trifocal eyeglasses. Preoperative patient selection and good counselling is extremely important to avoid unrealistic expectations and post-operative patient dissatisfaction. Acceptability for these lenses has become better and studies have shown good results in selected patients.
    In addition, there is an accommodating lens that was approved by the US FDA in 2003 and made by Eyeonics,[6] now Bausch & Lomb. The Crystalens is on struts and is implanted in the eye’s lens capsule, and its design allows the lens’ focusing muscles to move it back and forth, giving the patient natural focusing ability.

    Artificial intraocular lenses (IOLs) are used to replace the eye’s natural lens that is removed during cataract surgery. These lenses have been increasing in popularity since the 1960s, but it was not until 1981 that the first U.S. Food and Drug Administration (FDA) approval for this type of product was issued. The development of IOLs brought about an innovation as patients previously did not have their natural lens replaced and as a result had to wear very thick eyeglasses or some special type of contact lenses. Presently[when?], IOLs are especially designed for patients with different vision problems. The main types of IOLs that now exist are divided into monofocal and multifocal lenses.

    The monofocal intraocular lenses are the traditional ones, which provide vision at one distance only: far, intermediate, or near. Patients who choose these lenses over the more developed types will probably need to wear eyeglasses or contact lenses for reading or using the computer. These intraocular lenses are usually spherical, and they have their surface uniformly curved.[medical citation needed]

    The multifocal intraocular lens is one of the newest types of such lenses. They are often referred to as “premium” lenses because they are multifocal and accommodative, and allow the patient to visualize objects at more than one distance, removing the need to wear eyeglasses or contact lenses. Premium intraocular lenses are those used in correcting presbyopia or astigmatism. Premium intraocular lenses are more expensive and are typically not covered, or not fully covered, by health insurance, as their additional benefits are considered a luxury and not a medical necessity. An accommodative intraocular lens implant has only one focal point, but it acts as if it is a multifocal IOL. The intraocular lens was designed with a hinge similar to the mechanics of the eye’s natural lens.[medical citation needed]

    The intraocular lenses used in correcting astigmatism are called toric, and have been FDA approved since 1998. The STAAR Surgical Intraocular Lens was the first such lens ever developed in the United States and it may correct up to 3.5 diopters. A different model of toric lenses is created by Alcon and may correct up to 3 diopters of astigmatism. In order to achieve the most benefit from a toric lens, the surgeon must rotate the lens to be on axis with the patient’s astigmatism. Intraoperative wavefront analysis, such as that provided by the ORA System developed by Wavetec Visions Systems, can be used to assist the doctor in toric lens placement and minimize astigmatic errors.[medical citation needed]

    Cataract surgery may be performed to correct vision problems in both eyes, and in these cases, patients are usually advised to consider monovision. This procedure involves inserting in one eye an intraocular lens that provides near vision and in the other eye an IOL that provides distance vision. Although most patients can adjust to having implanted monofocal lenses in both eyes, some cannot and may experience blurred vision at both near and far distances. IOLs that emphasize distance vision may be mixed with IOLs that emphasize intermediate vision in order to achieve a type of modified monovision. Bausch and Lomb developed in 2004 the first aspheric IOLs, which provide better contrast sensitivity by having their periphery flatter than the middle of the lens. However, some cataract surgeons have questioned the benefits of aspheric IOLs, because the contrast sensitivity benefit may not last in older patients.[medical citation needed]

    Some of the newly-launched IOLs are able to provide ultraviolet and blue light protection. The crystalline lens of the eye filters these potentially harmful rays and many premium IOLs are designed to undertake this task as well. According to a few studies though, these lenses have been associated with a decrease in vision quality.[citation needed]

    Another type of intraocular lense is the light-adjustable one which is still[when?] undergoing FDA clinical trials. This particular type of IOL is implanted in the eye and then treated with light of a certain wavelength in order to alter the curvature of the lens.

    In some cases, surgeons may opt for inserting an additional lens over the already implanted one. This type of IOLs procedures are called “piggyback” IOLs and are usually considered an option whenever the lens result of the first implant is not optimal. In such cases, implanting another IOL over the existent one is considered safer than replacing the initial lens. This approach may also be used in patients who need high degrees of vision correction.

    No matter which IOL is used, the surgeon will need to select the appropriate power of IOL (much like an eyeglass prescription) to provide the patient with the desired refractive outcome. Traditionally, doctors use preoperative measurements including corneal curvature, axial length, and white to white measurements to estimate the required power of the IOL. These traditional methods include several formulas including Hagis, Hoffer Q, Holladay 1, Holladay 2, and SRK/T, to name a few. Refractive results using traditional power calculation formulas leave patients within 0.5D of target (correlates to 20/25 when targeted for distance) or better in 55% of cases and within 1D (correlates to 20/40 when targeted for distance) or better in 85% of cases. Recent developments in interoperative wavefront technology such as the ORA System from Wavetec Vision Systems, have demonstrated in studies, power calculations that provide improved outcomes, yielding 80% of patients within 0.5D (20/25 or better).

    Statistically, cataract surgery and IOL implantation seem to be procedures with the safest and highest success rates when it comes to eye care. However, as with any other type of surgery, it implies certain risks. The cost is another important aspect of these lenses. Although most insurance companies cover the costs of traditional IOLs, patients may need to pay the price difference if they choose the more expensive premium ones.

    Preoperative evaluation

    An eye examination or pre-operative evaluation by an eye surgeon is necessary to confirm the presence of a cataract and to determine if the patient is a suitable candidate for surgery. The patient must fulfill certain requirements such as:

    The degree of reduction of vision due, at least in large part, to the cataract should be evaluated. While the existence of other sight-threatening diseases, such as age-related macular degeneration or glaucoma, does not preclude cataract surgery, less improvement may be expected in their presence.
    The eyes should have a normal pressure, or any pre-existing glaucoma should be adequately controlled with medications. In cases of uncontrolled glaucoma, a combined cataract-glaucoma procedure (Phaco-trabeculectomy) can be planned and performed.
    The pupil should be adequately dilated using eyedrops; if pharmacologic pupil dilation is inadequate, procedures for mechanical pupillary dilatation may be needed during the surgery.
    The patients with retinal detachment may be scheduled for a combined vitreo-retinal procedure, along with PC-IOL implantation.
    In addition, it has recently been shown that patients taking tamsulosin (Flomax), a common drug for enlarged prostate, are prone to developing a surgical complication known as intraoperative floppy iris syndrome (IFIS), which must be correctly managed to avoid the complication posterior capsule rupture; however, prospective studies have shown that the risk is greatly reduced if the surgeon is informed of the patient’s history with the drug beforehand, and has appropriate alternative techniques prepared.[7]
    A Cochrane Review of three randomized clinical trials including over 21,500 cataract surgeries examined whether routine preoperative medical testing resulted in a reduction of adverse events during surgery.[8][needs update] Results showed that performing preoperative medical testing did not result in a reduction of risk of intraoperative or postoperative medical adverse events, compared to surgeries with no or limited preoperative testing.

    Operation procedure

    The surgical procedure in phacoemulsification for removal of cataract involves a number of steps. Each step must be carefully and skillfully performed in order to achieve the desired result. The steps may be described as follows:

    Anaesthesia;
    Exposure of the eyeball using an eyelid speculum;
    Entry into the eye through a minimal incision (corneal or scleral);
    Viscoelastic injection to stabilize the anterior chamber and to help maintain the eye pressurization;
    Capsulorhexis;
    Hydrodissection pie;
    Hydro-delineation;
    Ultrasonic destruction or emulsification of the cataract after nuclear cracking or chopping (if needed), careful aspiration of the remaining lens cortex (outer layer of lens) material from the capsular bag, capsular polishing (if needed);
    Implantation of the, usually foldable, intraocular lens (IOL);
    Viscoelastic removal;
    Wound sealing / hydration (if needed).
    The pupil is dilated using drops (if the IOL is to be placed behind the iris) to help better visualise the cataract. Pupil-constricting drops are reserved for secondary implantation of the IOL in front of the iris (if the cataract has already been removed without primary IOL implantation). Anesthesia may be placed topically (eyedrops) or via injection next to (peribulbar) or behind (retrobulbar) the eye. Oral or intravenous sedation may also be used to reduce anxiety. General anesthesia is rarely necessary, but may be employed for children and adults with particular medical or psychiatric issues. The operation may occur on a stretcher or a reclining examination chair. The eyelids and surrounding skin will be swabbed with disinfectant. The face is covered with a cloth or sheet, with an opening for the operative eye. The eyelid is held open with a speculum to minimize blinking during surgery. Pain is usually minimal in properly anesthetised eyes, though a pressure sensation and discomfort from the bright operating microscope light is common. The ocular surface is kept moist using sterile saline eye drops or methylcellulose viscoelastic. The discission into the lens of the eye is performed at or near where the cornea and sclera meet (limbus = corneoscleral junction). Advantages of the smaller incision include use of few or no stitches and shortened recovery time.[1][9]

    A capsulotomy (rarely known as cystotomy) is a procedure to open a portion of the lens capsule, using an instrument called a cystotome.[10] An anterior capsulotomy refers to the opening of the front portion of the lens capsule, whereas a posterior capsulotomy refers to the opening of the back portion of the lens capsule. In phacoemulsification, the surgeon performs an anterior continuous curvilinear capsulorhexis, to create a round and smooth opening through which the lens nucleus can be emulsified and the intraocular lens implant inserted.

    Following cataract removal (via ECCE or phacoemulsification, as described above), an intraocular lens is usually inserted. After the IOL is inserted, the surgeon checks that the incision does not leak fluid. This is a very important step, since wound leakage increases the risk of unwanted microorganisms gaining access into the eye and predisposing it to endophathalmitis. An antibiotic/steroid combination eye drop is put in and an eye shield may be applied on the operated eye, sometimes supplemented with an eye patch.

    Antibiotics may be administered pre-operatively, intra-operatively, and/or post-operatively. Frequently a topical corticosteroid is used in combination with topical antibiotics post-operatively.

    Most cataract operations are performed under a local anaesthetic, allowing the patient to go home the same day. The use of an eye patch may be indicated, usually for about some hours, after which the patient is instructed to start using the eyedrops to control the inflammation and the antibiotics that prevent infection. Lens and cataract procedures are commonly performed in an outpatient setting; in the United States, 99.9% of lens and cataract procedures were done in an ambulatory setting in 2012.[11]

    Occasionally, a peripheral iridectomy may be performed to minimize the risk of pupillary block glaucoma. An opening through the iris can be fashioned manually (surgical iridectomy) or with a laser (called Nd-YAG laser iridotomy). The laser peripheral iridotomy may be performed either prior to or following cataract surgery.

    The iridectomy hole is larger when done manually than when performed with a laser. When the manual surgical procedure is performed, some negative side-effects may occur, such as that the opening of the iris can be seen by others (aesthetics), and the light can fall into the eye through the new hole, creating some visual disturbances. In the case of visual disturbances, the eye and brain often learn to compensate and ignore the disturbances over a couple of months. Sometimes the peripheral iris opening can heal, which means that the hole ceases to exist. This is the reason that the surgeon sometimes makes two holes, so that at least one hole is kept open.

    After the surgery, the patient is instructed to use anti-inflammatory and antibiotic eye-drops for up to two weeks (depending on the inflammation status of the eye and some other variables). The eye surgeon will judge, based on each patient’s idiosyncrasies, the time length to use the eye drops. The eye will be mostly recovered within a week, and complete recovery should be expected in about a month. The patient should not participate in contact/extreme sports until cleared to do so by the eye surgeon.

    Complications
    Edit
    Complications after cataract surgery are relatively uncommon.

    PVD — Posterior vitreous detachment does not directly threaten vision. Even so, it is of increasing interest because the interaction between the vitreous body and the retina might play a decisive role in the development of major pathologic vitreoretinal conditions. PVD may be more problematic with younger patients, since many patients older than 60 have already gone through PVD. PVD may be accompanied by peripheral light flashes and increasing numbers of floaters.

    Slit lamp photo of IOL showing Posterior capsular opacification (PCO) visible a few months after implantation of Intraocular lens in eye, seen on retroillumination
    PCO — Some people can develop a posterior capsular opacification (PCO), also called an after-cataract. As a physiological change expected after cataract surgery, the posterior capsular cells undergo hyperplasia and cellular migration, showing up as a thickening, opacification and clouding of the posterior lens capsule (which is left behind when the cataract was removed, for placement of the IOL). This may compromise visual acuity and the ophthalmologist can use a device to correct this situation. It can be safely and painlessly corrected using a laser device to make small holes in the posterior lens capsule of the crystalline. It usually is a quick outpatient procedure that uses a Nd-YAG laser (neodymium-yttrium-aluminum-garnet) to disrupt and clear the central portion of the opacified posterior lens capsule (posterior capsulotomy). This creates a clear central visual axis for improving visual acuity.[12] In very thick opacified posterior capsules, a surgical (manual) capsulectomy is the surgical procedure performed. A YAG capsulotomy is, however, a factor which must be taken in consideration in the event of IOL replacement as vitreous can migrate toward the anterior chamber through the opening hitherto occluded by the IOL.
    Posterior capsular tear may be a complication during cataract surgery. The rate of posterior capsular tear among skilled surgeons is around 2% to 5%. It refers to a rupture of the posterior capsule of the natural lens. Surgical management may involve anterior vitrectomy and, occasionally, alternative planning for implanting the intraocular lens, either in the ciliary sulcus, in the anterior chamber (in front of the iris), or, less commonly, sutured to the sclera.
    Retinal detachment is an uncommon complication of cataract surgery, which may occur weeks, months, or even years later.
    Toxic Anterior Segment Syndrome or TASS is a non-infectious inflammatory condition that may occur following cataract surgery. It is usually treated with topical corticosteroids in high dosage and frequency.
    Endophthalmitis is a serious infection of the intraocular tissues, usually following intraocular surgery, or penetrating trauma. There is some concern that the clear cornea incision might predispose to the increase of endophthalmitis but there is no conclusive study to corroborate this suspicion.
    Glaucoma may occur and it may be very difficult to control. It is usually associated with inflammation, specially when little fragments or chunks of the nucleus get access to the vitreous cavity. Some experts recommend early intervention when this condition occurs (posterior pars plana vitrectomy). Neovascular glaucoma may occur, specially in diabetic patients. In some patients, the intraocular pressure may remain so high that blindness may ensue.
    Swelling or edema of the central part of the retina, called macula, resulting in macular edema, can occur a few days or weeks after surgery. Most such cases can be successfully treated. Preventative use of nonsteroidal anti-inflammatory drugs has been reported to reduce the risk of macular edema to some extent.[13]
    Other possible complications include: Swelling or edema of the cornea, sometimes associated with cloudy vision, which may be transient or permanent (pseudophakic bullous keratopathy). Displacement or dislocation of the intraocular lens implant may rarely occur. Unplanned high refractive error (either myopic or hypermetropic) may occur due to error in the ultrasonic biometry (measure of the length and the required intraocular lens power). Cyanopsia, in which the patient sees everything tinted with blue, often occurs for a few days, weeks or months after removal of a cataract. Floaters commonly appear after surgery.

    History
    Edit
    Ancient Greece
    Edit
    Galen of Pergamon (c. 2nd century CE), a prominent Greek physician, surgeon and philosopher, performed an operation similar to modern cataract surgery. Using a needle-shaped instrument, Galen attempted to remove a cataract-affected lens.[14][15] Although many 20th century historians have claimed that Galen believed the lens to be in the exact center of the eye, Galen actually understood that the crystalline lens is located in the anterior aspect of the human eye.[16]

    India
    Edit
    A form of cataract surgery, now known as ‘couching’ (a dangerous method of dislodging the lens with a sharp object, yielding blindness in 70% of cases, and very little improvement in the rest), was found in ancient India and subsequently introduced to other countries by the Indian physician Sushruta (ca. 3rd century CE[17][18]), who described it in his work the Compendium of Sushruta or Sushruta Samhita. The Uttaratantra section of the Compendium, chapter 17, verses 55–69, describes an operation in which a curved needle was used to push the opaque phlegmatic matter (kapha in Sanskrit) in the eye out of the way of vision. The phlegm was then blown out of the nose. The eye would later be soaked with warm clarified butter and then bandaged. Here is translation from the original Sanskrit:

    vv.55-56: Now procedure of surgical operation of ślaiṣmika liṅganāśa (cataract) will be described. It should be taken up (for treatment) if the diseased portion in the pupillary region is not shaped like half moon, sweat drop or pearl: not fixed, uneven and thin in the centre, streaked or variegated and is not found painful or reddish.

    vv. 57-61ab: In moderate season, after unction and sudation, the patient should be positioned and held firmly while gazing at his nose steadily. Now the wise surgeon leaving two parts of white circle from the black one towards the outer canthus should open his eyes properly free from vascular network and then with a barley-tipped rod-like instrument held firmly in hand with middle, index and thumb fingers should puncture the natural hole-like point with effort and confidence not below, above or in sides. The left eye should be punctured with right hand and vice-versa. When punctured properly a drop of fluid comes out and alsoe there is some typical sound.

    vv. 61bc-64ab: Just after puncturing, the expert should irrigate the eye with breast-milk and foment it from outside with vāta-[wind-]alleviating tender leaves, irrespective of doṣa [defect] being stable or mobile, holding the instrument properly in position. Then the pupillary circle should be scraped with the tip of the instrument while the patient, closing the nostril of the side opposite to the punctured eye, should blow so that kapha [phlegm] located in the region be eliminated.

    vv. 64cd-67: When pupillary region becomes clear like cloudless sun and is painless, it should be considered as scraped properly. (If doṣa [defect] cannot be eliminated or it reappears, puncturing is repeated after unction and sudation.) When the sights are seen properly the śalākā [probe] should be removed slowly, eye anointed with ghee and bandaged. Then the patient :should lie down in supine position in a peaceful chamber. He should avoid belching, coughing, sneezing, spitting and shaking during the operation and thereafter should observe the restrictions as after intake of sneha [oil].

    v.68: Eye should be washed with vāta-[wind-]alleviating decoctions after every three days and to eliminate fear of (aggravation of) vāyu [wind], it should also be fomented as mentioned before (from outside and mildly).

    v.69: After observing restrictions for ten days in this way, post-operative measures to normalise vision should be employed along with light diet in proper quantity.[19]

    The removal of cataracts by surgery was also introduced into China from India, and flourished in the Sui (AD 581–618) and Tang dynasties (AD 618–907).[20]

    Europe and the Islamic world
    Edit
    The first references to cataract and its treatment in Europe are found in 29 AD in De Medicinae, the work of the Latin encyclopedist Aulus Cornelius Celsus, which also describes a couching operation.[citation needed]

    Couching continued to be used throughout the Middle Ages and is still used in some parts of Africa and in Yemen.[21] However, couching is an ineffective and dangerous method of cataract therapy, and often results in patients remaining blind or with only partially restored vision.[21] For the most part, it has now been replaced by extracapsular cataract surgery and, especially, phacoemulsification.[citation needed]

    The lens can also be removed by suction through a hollow instrument. Bronze oral suction instruments have been unearthed that seem to have been used for this method of cataract extraction during the 2nd century AD.[22] Such a procedure was described by the 10th-century Persian physician Muhammad ibn Zakariya al-Razi, who attributed it to Antyllus, a 2nd-century Greek physician. The procedure “required a large incision in the eye, a hollow needle, and an assistant with an extraordinary lung capacity”.[23] This suction procedure was also described by the Iraqi ophthalmologist Ammar Al-Mawsili, in his Choice of Eye Diseases, also written in the 10th century.[23] He presented case histories of its use, claiming to have had success with it on a number of patients.[23] Extracting the lens has the benefit of removing the possibility of the lens migrating back into the field of vision.[24] A later variant of the cataract needle in 14th-century Egypt, reported by the oculist Al-Shadhili, used a screw to produce suction. It is not clear, however, how often this method was used as other writers, including Abu al-Qasim al-Zahrawi and Al-Shadhili, showed a lack of experience with this procedure or claimed it was ineffective.[23][verification needed]

    Eighteenth century and later
    Edit
    In 1748, Jacques Daviel was the first modern European physician to successfully extract cataracts from the eye. In America, an early form of surgery known as cataract couching may have been performed in 1611,[25] and cataract extraction was most likely performed by 1776.[26] Cataract extraction by aspiration of lens material through a tube to which suction is applied was performed by Philadelphia surgeon Philip Syng Physick in 1815.[27]

    In the 1940s, Harold Ridley introduced the concept of implantation of the intraocular lens which permitted more efficient and comfortable visual rehabilitation possible after cataract surgery. The implantation of a foldable intraocular lens is the procedure considered the state-of-the-art.[citation needed]

    In 1967, Charles Kelman introduced phacoemulsification, a technique that uses ultrasonic waves to emulsify the nucleus of the crystalline lens in order to remove the cataracts without a large incision. This new method of surgery decreased the need for an extended hospital stay and made the surgery ambulatory. Patients who undergo cataract surgery hardly complain of pain or even discomfort during the procedure. However patients who have topical anesthesia, rather than peribulbar block anesthesia, may experience some discomfort.[citation needed]

    According to surveys of members of the American Society of Cataract and Refractive Surgery, approximately 2.85 million cataract procedures were performed in the United States during 2004 and 2.79 million in 2005.[28]

    In India, modern surgery with intraocular lens insertion in government- and NGO-sponsored Eye Surgical camps has replaced older surgical procedures.[citation needed] In rare cases, infections have caused blindness among some of the patients in mass free eye camps in India.[29]

    Society and culture
    Edit
    Usage in the UK
    Edit
    In the UK the practice of the various NHS healthcare providers in referring people with cataracts to surgery varied widely as of 2017, with many of the providers only referring people with moderate or severe vision loss, and often with delays.[30] This is despite guidance issued by the NHS executive in 2000 urging providers to standardize care, streamline the process, and increase the number of cataract surgeries performed in order to meet the needs of the aging population.[31]

    See also
    References
    Edit
    Notes
    Edit
    Extracapsular Cataract Extraction – Definition, Purpose, Demographics, Description, Diagnosis/preparation, Aftercare, Risks, Normal results, Morbidity and mortality rates, Alternatives Encyclopedia of Surgery: A Guide for Patients and Caregivers
    Alió, JL; Abdou, AA; Puente, AA; Zato, MA; Nagy, Z (June 2014). “Femtosecond laser cataract surgery: updates on technologies and outcomes”. Journal of Refractive Surgery. 30 (6): 420–7. doi:10.3928/1081597x-20140516-01. PMID 24972409.
    Popovic M, Campos-Möller X, Schlenker MB, Ahmed II (2016). “Efficacy and Safety of Femtosecond Laser-Assisted Cataract Surgery Compared with Manual Cataract Surgery: A Meta-Analysis of 14 567 Eyes”. Ophthalmology. 123 (10): 2113–26. doi:10.1016/j.ophtha.2016.07.005. PMID 27538796.
    Cryotherapy for cataracts. Encyclopedia of Surgery
    Meadow, Norman B. Cryotherapy: A fall from grace, but not a crash]. Ophthalmology Times. October 15, 2005.
    New Device Approval – CrystaLens Model AT-45 Accommodating IOL – P030002. U.S. Food and Drug Administration.
    Charters, Linda Anticipation is key to managing intra-operative floppy iris syndrome Archived 2006-10-22 at the Wayback Machine. Ophthalmology Times. June 15, 2006.
    Keay L, Lindsley K, Tielsch J, Katz J, Schein O (2012). “Routine preoperative medical testing for cataract surgery”. Cochrane Database Syst Rev. 3 (3): CD007293. doi:10.1002/14651858.CD007293.pub3. PMC 4261928. PMID 22419323.
    Surgery Encyclopedia – Phacoemulsification for cataracts
    Capsulorhexis using a cystotome needle during cataract surgery Archived 2008-08-26 at the Wayback Machine
    Wier LM, Steiner CA, Owens PL (February 2015). “Surgeries in Hospital-Owned Outpatient Facilities, 2012”. HCUP Statistical Brief #188. Rockville, MD: Agency for Healthcare Research and Quality.
    Surgery Encyclopedia – Laser posterior capsulotomy
    Lim, Blanche X.; Lim, Chris Hl; Lim, Dawn K.; Evans, Jennifer R.; Bunce, Catey; Wormald, Richard (2016). “Prophylactic non-steroidal anti-inflammatory drugs for the prevention of macular oedema after cataract surgery”. The Cochrane Database of Systematic Reviews. 11: CD006683. doi:10.1002/14651858.CD006683.pub3. ISSN 1469-493X. PMID 27801522.
    Keele, K. D. (1963). “Galen: On Anatomical Procedures: the Later Books”. Med Hist. 7 (1): 85–87. doi:10.1017/s002572730002799x. PMC 1034789.
    Lois N. Magner (1992). A History of Medicine. CRC Press. p. 91.
    Leffler CT, Hadi TM, Udupa A, Schwartz SG, Schwartz D (2016). “A medieval fallacy: the crystalline lens in the center of the eye”. Clinical Ophthalmology. 2016 (10): 649–662. doi:10.2147/OPTH.S100708. PMC 4833360. PMID 27114699.
    P. V. Sharma, Sushruta-Samhita (Varanasi: Caukhambha Visvabharati, 2000), vol. 1, p. iv.
    Meulenbeld, G. Jan (1999–2002). A History of Indian Medical Literature. Groningen: Forsten.
    Sharma, Priya Vrat (2001). Suśruta-Saṃhitā with English translation of text and Ḍalhaṇa’s commentary along with critical notes. Vol ĪI (Kalpasthāna and Uttaratantra). Varanasi, India: Chaukhambha Visvabharati Oriental. pp. 202–4.
    Deshpande, Vijaya (2000). “Ophthalmic surgery: a chapter in the history of Sino-Indian medical contacts”. Bulletin of the School of Oriental and African Studies. 63 (3): 370–388. doi:10.1017/S0041977X00008454. See also Deshpande, Vijaya (1999). “Indian influences on early Chinese ophthalmology: glaucoma as a case study”. Bulletin of the School of Oriental and African Studies. 62 (22): 306–322. doi:10.1017/S0041977X00016724.
    ‘Couching’ for cataracts remains a persistent problem in Yemen Archived 2011-07-26 at the Wayback Machine, EuroTimes, September 2005, p. 11.
    Factors influencing the genesis of neurosurgical technology, William C. Bergman, M.D., Raymond A. Schulz, M.Sc., and Deanna S. Davis, M.S., P.A.-C., Neurosurgical Focus 27, #3 (September 2009), E3; doi:10.3171/2009.6.FOCUS09117.
    Savage-Smith Emilie (2000). “The Practice of Surgery in Islamic Lands: Myth and Reality”. Social History of Medicine. 13 (2): 307–321 [318–9]. doi:10.1093/shm/13.2.307.
    Finger, Stanley (1994). Origins of Neuroscience: A History of Explorations Into Brain Function. Oxford University Press. p. 70. ISBN 978-0-19-514694-3.
    Leffler CT, Wainsztein RD (2016). “The first cataract surgeons in Latin America (1611-1830)”. Clinical Ophthalmology. 10: 679–694. doi:10.2147/OPTH.S105825. PMC 4841434. PMID 27143845.
    Leffler CT, Schwartz SG, Grzybowski A, Braich PS (2015). “The first cataract surgeons in Anglo-America”. Survey of Ophthalmology. 60 (1): 86–92. doi:10.1016/j.survophthal.2014.08.002. PMC 4262555. PMID 25444521.
    Leffler CT, Letocha CE, Pierson K, Schwartz SG (2017). “Aspiration of cataract in 1815 in Philadelphia, Pennsylvania”. Digital Journal of Ophthalmology. 23 (4): 4–7. doi:10.5693/djo.01.2017.10.001. PMC 5791631. PMID 29403333.
    American Academy of Ophthalmology reference[permanent dead link]
    “India cataracts scandal: Arrests over ‘botched’ surgery”. BBC. 5 December 2014.
    “Two thirds of eye units restricting access to cataract surgery”. OnMedica. 10 November 2017. Retrieved 28 December 2017.
    “Action on Cataracts Good Practice Guidance” (PDF). NHS Executive via the Royal College of Ophthalmologists. January 2000., referenced in “Context: Guideline for Cataracts in adults”. NICE. October 2017.
    Bibliography
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    Finger, Stanley (2001). Origins of Neuroscience: A History of Explorations Into Brain Function. Oxford University Press. ISBN 978-0-19-514694-3.
    Lade, Arnie; Svoboda, Robert (2000). Chinese Medicine and Ayurveda. Motilal Banarsidass. ISBN 978-81-208-1472-1.
    Frampton, Geoff; Harris, Petra; Cooper, Keith; Lotery, Andrew; Shepherd, Jonathan (2014). “The clinical effectiveness and cost-effectiveness of second-eye cataract surgery: a systematic review and economic evaluation”. Health Technology Assessment. Southampton UK: NIHR Journals Library. 18.68.
    Prajna, N. Venkatesh; Ravilla, Thulasiraj D.; Srinivasan, Sathish (2015). “Ch: 11. Cataract Surgery”. In Debas, H.T.; Donkor, P.; Gawande, A.; Jamison, D.T.; Kruk, M.E.; Mock, C.N. Essential Surgery. Disease Control Priorities. 1 (3rd ed.). The International Bank for Reconstruction and Development / The World Bank. ISBN 978-1-4648-0346-8.